The Moses H. Cone Memorial Hospital Level II Trauma Center  serves the Greater Greensboro community by providing superior care to people who have sustained severe injuries. The Trauma Center began in 2000 and was recertified by the State of North Carolina until 2009.

If a patient is admitted by the Trauma Service, it is usually because there are at least two organ systems injured (for example, a head injury and a fractured rib), there is a single organ injury that falls under the care of the general surgeon or there are medical problems that complicate the care of the traumatically injured patient.

Trauma surgeons are specially trained general surgeons. The trauma team coordinates different medical specialties, including, but not limited to, neurosurgery, orthopedic surgery, plastic surgery, oral and maxillofacial surgery, physical therapy, occupational therapy, speech therapy and rehabilitation services to optimize care.

Patients are usually admitted from the emergency room. The trauma surgeon and the trauma physician assistants (PAs) evaluate the patient and decide on the best course of immediate action. Once the patient is in the hospital, the trauma surgeon and often the trauma PA will see the patient daily. This almost always occurs between 7 and 11 a.m. The sicker patients (for example, those in the intensive care units) are seen first. Families who want to speak with the clinicians should be in the patient's room during this time. Other specialists and therapists will see the patients as their schedules allow.

Patients progress from the intensive care unit either to an acute care or 'step-down' bed or directly to a regular hospital room. From there, planning begins for discharge, either to home, to a rehabilitation service at the hospital, or to a skilled nursing facility. During this process, there will likely be diet and movement restrictions, which will be reduced as the patient improves.